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Adverse events by system organ class and preferred term

Source: R/builders-table.R
tbl_ae.Rd

Counts subjects with at least one event. SOCs and PTs are sorted by decreasing frequency, with ties broken alphabetically. Denominators come from adsl when given, otherwise from adae.

Usage

tbl_ae(
  adae,
  adsl = NULL,
  trt_var = "TRT01A",
  soc_var = "AESOC",
  pt_var = "AEDECOD",
  teae_flag = "TRTEMFL",
  config = NULL
)

Arguments

adae

Adverse-event data.

adsl

Optional subject-level data for denominators.

trt_var

Treatment variable (resolved with tlf_resolve_trt()).

soc_var, pt_var

SOC and PT columns.

teae_flag

Treatment-emergent flag column ("Y" rows are kept); NULL keeps all events.

config

A tlf_config(); NULL resolves through tlf_get_config().

Value

A tlf_table.

See also

Other table builders: tbl_ae_severity(), tbl_demographics(), tbl_disposition(), tbl_eff(), tbl_listing(), tbl_shift(), tbl_tte()

Examples

tbl_ae(ex_adae, ex_adsl)
#> <tlf_table> 11 row(s) x 5 column(s)
#>  System Organ Class / Preferred Term    Drug 10 mg (N=20) Drug 20 mg (N=20)
#>  Subjects with at least one TEAE        16 (80.0%)        17 (85.0%)       
#>  NERVOUS SYSTEM DISORDERS               9 (45.0%)         11 (55.0%)       
#>    DIZZINESS                            6 (30.0%)         7 (35.0%)        
#>    HEADACHE                             6 (30.0%)         7 (35.0%)        
#>  GASTROINTESTINAL DISORDERS             8 (40.0%)         12 (60.0%)       
#>    DIARRHOEA                            4 (20.0%)         6 (30.0%)        
#>    NAUSEA                               4 (20.0%)         6 (30.0%)        
#>  INFECTIONS AND INFESTATIONS            6 (30.0%)         4 (20.0%)        
#>    NASOPHARYNGITIS                      6 (30.0%)         4 (20.0%)        
#>  SKIN AND SUBCUTANEOUS TISSUE DISORDERS 2 (10.0%)         2 (10.0%)        
#>    RASH                                 2 (10.0%)         2 (10.0%)        
#>  Placebo (N=20) Total (N=60)
#>  17 (85.0%)     50 (83.3%)  
#>  11 (55.0%)     31 (51.7%)  
#>  8 (40.0%)      21 (35.0%)  
#>  5 (25.0%)      18 (30.0%)  
#>  6 (30.0%)      26 (43.3%)  
#>  5 (25.0%)      15 (25.0%)  
#>  3 (15.0%)      13 (21.7%)  
#>  6 (30.0%)      16 (26.7%)  
#>  6 (30.0%)      16 (26.7%)  
#>  4 (20.0%)      8 (13.3%)   
#>  4 (20.0%)      8 (13.3%)   
#> Note: Subjects are counted once per SOC and once per preferred term.